Central line associated bloodstream infections in hospitalised children in Greece before and after implementation of a prevention bundle

Katerina Mougkou, Despoina Gkentzi, Georgia Kourlaba, Sofia Kouni, Ioannis Kopsidas, Charalampia Nteli, Theoklis Zaoutis, Susan Coffin

Int J Infect Control 2014, v11:i3 doi: 10.3396/IJIC.v11i3.019.15

Abstract 

Data on central line (CL) - associated bloodstream infections (CLABSIs) in neonates and children in Greece are limited. In this study we aimed to assess the epidemiology and microbiology of CLABSIs in children’s hospitals in Greece using an active surveillance system and to assess the impact of a central line bundle on the incidence of CLABSIs.

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Perioperative antimicrobial prophylaxis in pediatric patients in Greece: Compliance with guidelines and impact of an educational intervention

Dimopoulou A, Kourlaba G, Psarris A, Coffin S, Spoulou V, Zaoutis T. J Pediatr Surg.

2015 Dec 1. pii: S0022-3468(15)00772-1. doi: 10.1016/j.jpedsurg.2015.11.017. [Epub ahead of print]

BACKGROUND/PURPOSE: Appropriate antimicrobial prophylaxis (PAP) prevents surgical site infections (SSI). The aim of this study was to evaluate the effectiveness of an educational intervention to improve adherence to PAP guidelines in pediatric patients.

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Variation in paediatric hospital antibiotic guidelines in Europe

Spyridis N, Syridou G, Goossens H, Versporten A, Kopsidas J, Kourlaba G, Bielicki J, Drapier N, Zaoutis T, Tsolia M, Sharland M; ARPEC Project Group Members. Arch Dis Child.

2016 Jan;101(1):72-6. doi: 10.1136/archdischild-2015-308255. Epub 2015 Sep 28.

OBJECTIVE: To assess the availability and source of guidelines for common infections in European paediatric hospitals and determine their content and characteristics.

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Antibiotic prescribing and expenditures in outpatient adults in Greece, 2010 to 2013: evidence from real-world practice

Kourlaba G, Gkrania-Klotsas E, Kourkouni E, Mavrogeorgos G, Zaoutis TE.

Euro Surveill. 2016 Jun 30;21(26). doi: 10.2807/1560-7917.ES.2016.21.26.30266.

Abstract: We provide a representative analysis of antibiotic prescribing, identify factors associated with broad-spectrum antibiotic prescribing and assess the costs associated with antibiotic use in adult outpatients in Greece. Outpatient antibiotic prescriptions for patients older than 19 years between 2010 and 2013 in Greece were extracted from the IMS Health Xponent database. Prescribing rate and total cost for prescribed antibiotics were calculated.

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Antibiotic prescribing and expenditures in outpatient paediatrics in Greece, 2010-13

Kourlaba G, Kourkouni E, Spyridis N, Gerber JS, Kopsidas J, Mougkou K, Lourida A, Zaoutis TE. J Antimicrob Chemother.

2015 Aug;70(8):2405-8. doi: 10.1093/jac/dkv091. Epub 2015 Apr 16.

OBJECTIVES: The objectives of this study were to provide a nationally representative analysis of antibiotic prescribing in outpatient paediatrics and to assess overall and class-specific antibiotic costs in Greece.

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