Origins & Mission

The Center for Clinical Epidemiology and Outcomes Research (CLEO) was founded in 2011 under the auspices of the 1st and 2nd Pediatric Department of the National and Kapodistrian University of Athens, thanks to a grant from the Stavros Niarchos Foundation. CLEO’s vision is to improve patient safety and the quality healthcare services provided by Greek hospitals, with emphasis on the prevention of hospital acquired infections and the judicious use of antibiotics. CLEO is operating as an non-governmental, non-profit organisation since October 2014.

From July 2012 through December 2015, CLEO implemented research and evaluation activities aimed at the prevention of hospital acquired infections and the judicious use of antibiotics in two tertiary Children’s Hospitals of Athens, “Aghia Sophia” and “Panagiotis and Aglaia Kyriakou”. Specifically, this work focused on the design and implementation of educational interventions on appropriate practices to improve the quality of the health services and increase the adoption of internationally established guidelines on daily clinical practice. The CLEO research team collaborated with specialized teaching, research, medical-nursing and administrative personnel, both from Greece and abroad, to design and implement these interventions, and to determine their effectiveness.

The encouraging results of the program generated optimism for the possibility of controlling and preventing hospital acquired infections and, consequently, for patient health outcomes. The success of this program, along with the increasingly recognized understanding that hospital acquired infections are largely preventable, attracted the interest of a number of health organizations that wished to support the program’s expansion. From January 2016 to December 2019, through the PHIG project, CLEO expanded its field of action, to include a wider range of pediatric hospitals as well as adult hospitals all over Greece, with the following activities:

  • Surveillance and prevention of the most common hospital acquired infections;
  • Surveillance and improvement of compliance to selected prevention practices; and
  • Surveillance of antibiotic use.

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CLEO was founded thanks to a grant of the “Stavros Niarchos” Foundation, which has supported its function as the main donator since 2011 and continues to do so today.