Mantadakis, E., Kopsidas, I., Coffin, S., Dimitriou, G., Gkentzi, D., Hatzipantelis, E., Kaisari, A., Kattamis, A., Kourkouni, E., Papachristidou, S., Papakonstantinou, E., Polychronopoulou, S., Roilides, E., Spyridis, N., Tsiodras, S., Tsolia, M. N., Tsopela, G.-C., Zaoutis, T. and Tragiannidis, A.
Antimicrobial Stewardship & Healthcare Epidemiology, Cambridge University Press, 2(1): e.71, http://doi.org/10.1017/ash.2022.43
Objective: We surveyed antimicrobials used in Greek pediatric hematology–oncology (PHO) and bone marrow transplant (BMT) units before and after an intervention involving education regarding the 2017 clinical practice guidelines (CPG) for the management of febrile neutropenia in children with cancer and hematopoietic stem-cell transplant recipients.
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Salmanton-Garcia J, Stewart FA, Heringer S, Koniordou M, Álvarez-Barco E, Argyropoulos CD, Themistolcleous SC, Valle-Simón P, Spivak O, Součková L, Merakou C, Mendonça MA, Davis RJ, Azzini AM, Askling HH, Vene S, Van Damme P, Steinbach A, Shiamakkides G, Seidel D, Olesen OF, Noula E, Macken A, Luís C, Leckler J, Launay O, Isitt C, Hellemans M, Frias-Iniesta J, Di Marzo R, Carcas AJ, Boustras G, Borobia AM, Barta I, Albus K, Akova M, Ochando J, Cohen-Kandli M, Cox RJ, Husa P, Jancoriene L, Mallon P, Marques L, Mellinghoff SC, Nauclér P, Tacconelli E, Beer-Tóth K, Zaoutis TE, Zeitlinger M, Cornely OA, Pana ZD and the VACCELERATE consortium.
Preprints with The Lancet, 2022 Jan, DOI: http://dx.doi.org/10.2139/ssrn.4016606 and SSRN: https://ssrn.com/abstract=4016606
Abstract
Background: The coronavirus disease 2019 (COVID-19) pandemic has demonstrated the key role that vaccines play against infectious diseases. Although clinical trials were rapidly established during this pandemic, identifying suitable study subjects can be challenging. For this reason, the University Hospital Cologne established a volunteer registry for participation in clinical trials first in Germany, which has now been incorporated into the European VACCELERATE clinical trials network and grew to a European Volunteer Registry. As such, VACCELERATE’s Volunteer Registry aims to become a common entry point for potential volunteers in future clinical trials in Europe. Methods Interested volunteers who would like to register for clinical trials in the VACCELERATE Volunteer Registry can access the registration questionnaire via http://www.vaccelerate.eu/volunteer-registry.
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Kopsidas I, Molocha NM, Kourkouni E, Coffin S, Gkentzi D, Chorianopoulou E, Dimitriou G, Kapetanaki A, Karavana G, Lithoxopoulou M, Polychronaki M, Roilides E, Triantafyllidou P, Triantafyllou C, Tsopela GC, Tsouvala E, Tsolia MN, Zaoutis T, Spyridis N; PHiG Investigators: Vassiliki Papaevangelou, Asimina Tsintoni, Vasiliki Soubasi-Griva, Marianna Skordala-Riti, Maria Theodoraki.
Eur J Pediatr., 2021 Oct, DOI: https://doi.org/10.1007/s00431-021-04282-x
Abstract
Aim: To assess the potential benefit from the implementation of the Kaiser Permanente early-onset sepsis calculator (EOS-C), in terms of antibiotic use and requested laboratory tests, in a network of neonatal intensive care units (NICUs) in Greece, and to determine the incidence of early-onset sepsis (EOS) in Greek NICUs, a prospective surveillance study was conducted in 7 NICUs between April 2018 and June 2019.
Methods: Data were collected for all newborns ≥ 34 weeks’ gestation receiving empiric antibiotic therapy within the first 3 days of life. The number of live births and positive blood or cerebrospinal fluid cultures within the first 3 days of life were used for calculation of EOS incidence. Evaluation of possible impact of implementing the calculator was done by comparing the clinicians’ recorded management to the calculator’s suggested course of action.
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Ioannis Kopsidas, Evangelia Chorianopoulou, Eleni Kourkouni, Christos Triantafyllou, Nafsika-Maria Molocha, Markela Koniordou, Stefania Maistreli, Christina - Grammatiki Tsopela, Stefania Maroudi-Manta, Dimitrios Filippou, Theoklis E. Zaoutis, Georgia Kourlaba
Pneumon, 2021 Jun, DOI: https://doi.org/10.18332/pne/136173
Abstract
Objectives: To assess the impact of the SARS-CoV-2 pandemic on the seasonal influenza vaccination attitudes in Greece and to identify factors associated with a positive change in participant’s choice to vaccinate against flu.
Methods: A cross-sectional nationwide survey (n=1,004) was conducted during between April 28, 2020 to May 03, 2020 using a mixed methodology for data collection: Computer Assisted Telephone Interviewing (CATI) and Computer Assisted web Interviewing (CAWI). A proportionate stratified by region systematic sampling procedure was used to ensure a nationally representative sample of the urban/rural population. Data were collected using a structured questionnaire consisting of four parts:1) demographics;2) knowledge about COVID-19;3) attitudes toward COVID-19; and 4) practices to control COVID-19 and vaccination against flu.
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Ioannis Kopsidas, Grammatiki-Christina Tsopela, Nafsika-Maria Molocha, Eleni Bouza,Elisavet Chorafa, Evangelia Chorianopoulou, Vasileios Giapros, Despoina Gkentzi, Theodoros Gkouvas, Anastasia Kapetanaki, Korina Karachristou, Georgia Karavana, Eleni Kourkouni, Georgia Kourlaba, Maria Lithoxopoulou, Vassiliki Papaevangelou, Maria Polychronaki, Emmanuel Roilides, Tania Siahanidou, Evangelia Stratiki, George A. Syrogiannopoulos, Christos Triantafyllou, Maria N. Tsolia, Emmanouela Tsouvala, Theoklis Zaoutis, Nikos Spyridis and Preventing Hospital-Acquired Infections in Greece (PHiG) Investigators
Antibiotics, 2021 Mar;Online. DOI:https://doi.org/10.3390/antibiotics10030275
Abstract
Antibiotics are commonly prescribed in Neonatal Intensive Care Units (NICU), where stewardship interventions are challenging. Lowering antibiotic consumption is desperately needed in Greece, a country with high antibiotic resistance rates. We sought to assess the effectiveness of a low-cost and -resource intervention to reduce antibiotic use in Greek NICUs implementing a “low-hanging fruit” approach. A prospective quasi-experimental study was conducted in 15/17 public NICUs in Greece (9/2016–06/2019).
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