Elisavet Chorafa, Elias Iosifidis, Sotirios Tsiodras, Athanasios Skoutelis, Eleni Kourkouni, Ioannis Kopsidas, Grammatiki-Christina Tsopela, Evangelia Chorianopoulou, Christos Triantafyllou, Georgia Kourlaba, Theoklis Zaoutis, Emmanuel Roilides, and the Preventing Hospital-Acquired Infections in Greece (PHiG) investigators
Infection Control & Hospital Epidemiology, 2020 Nov;Online. DOI:https://doi.org/10.1017/ice.2020.1276
Objective: To audit clinical practice and implement an intervention to promote appropriate use of perioperative antimicrobial prophylaxis (PAP).
Methods: This was a prospective multicenter before-and-after study, conducted in 7 surgical departments of 3 major Greek hospitalsActive PAP surveillance in adults undergoing elective surgical procedures was performed before and after implementation of a multimodal intervention. The surveillance monitored use of appropriate antimicrobial agent according to international and local guidelines, appropriate timing and duration of PAP, overall compliance with all 3 parameters and the occurrence of surgical site infections (SSIs). The intervention included education, audit, and feedback.
Ioannis Kopsidas, Stefania Vergnano, Nikos Spyridis, Theoklis Zaoutis, Sanjay Patel
The Pediatric Infectious Disease Journal, 2020 Jul;Online. DOI:https://doi.org/10.1097/inf.0000000000002835
Background:Misuse, overuse of antimicrobials and increasing rates of antimicrobial resistance are well-recognized problems throughout Europe. The aim of this survey was to describe the current pediatric antibiotic stewardship (PAS) landscape across Europe and identify gaps, in terms of national programs, networks and guidelines.
Methods: A survey of 17 questions was circulated in July 2019 among 24 European pediatric infectious disease researchers and clinicians, professors and heads of department on the existence of PAS programs, national networks and meetings, established competencies, metrics and guidelines.
Ioannis Kopsidas, Grammatiki-Christina Tsopela, Stefania Maroudi-Manta, Eleni Kourkouni, Dimitrios Charalampopoulos, Alexandra Sirogianni, Madeline E. Collins, Athanasia Lourida, Georgia Kourlaba, Theoklis E. Zaoutis, Susan E. Coffin
Vaccine, 2020 Jun;38(29):4609-4615. DOI:https://doi.org/10.1016/j.vaccine.2020.05.021
Background: Healthcare workers’ (HCW) seasonal influenza vaccination (SIV) is critical to prevent nosocomial influenza. However, HCW vaccination rates remain unacceptably low in many European institutions. A two-year three-step initiative was implemented at a tertiary-care pediatric hospital with 750 beds in Athens, Greece with the aim of increasing SIV among HCW.
Sofia Karagiannidou, Christos Triantafyllou, Theoklis E. Zaoutis, Vassiliki Papaevangelou, Nikolaos Maniadakis, Georgia Kourlaba
Infection Control & Hospital Epidemiology, 2020 Mar;Online. DOI:https://doi.org/10.1017/ice.2019.353
Objective: To estimate the attributable mortality, length of stay (LOS), and healthcare cost of pediatric and neonatal healthcare-acquired bloodstream infections (HA-BSIs).
Methods: A systematic search (January 2000–September 2018) was conducted in PubMed, Cochrane, and CINAHL databases. Reference lists of selected articles were screened to identify additional studies. Case–control or cohort studies were eligible for inclusion when full text was available in English and data for at least 1 of the following criteria were provided: attributable or excess LOS, healthcare cost, or mortality rate due to HA-BSI. Study quality was evaluated using the Critical Appraisal Skills Programme Tool (CASP). Study selection and quality assessment were conducted by 2 independent researchers, and a third researcher was consulted to resolve any disagreements. Fixed- or random-effect models, as appropriate, were used to synthesize data. Heterogeneity and publication bias were evaluated.
Vasiliki Triantafillou, Ioannis Kopsidas, Areti Kyriakousi, Theoklis E. Zaoutis, Julia E. Szymczak
Journal of Hospital Infection, 2020 Apr;104(4):552-559. DOI:https://doi.org/10.1016/j.jhin.2019.11.020
Background: Healthcare-associated infections (HAIs) in the neonatal intensive care unit (NICU) result in increased morbidity, mortality, and healthcare costs. Rates of HAIs in Greek NICUs are among the highest in Europe. There is a need to identify the factors that influence the transmission of HAIs and implementation of prevention interventions in this setting.
Aim:To understand healthcare workers’ perceptions about HAI prevention in Greek NICUs.