Active Surveillance for Central Line Associated Bloodstream Infections in Hospitalized Neonates in Greece

K. Mougkou, N. Anagnostatou, L. Baglatzi, M. Dilanas, D. Gkentzi, I. Grivea, K. Kaffe, K. Karachristou, A. Kontogianni, L. Lianou, A. Mpilali, C. Petropoulou, Z. Stratiki, I. Zorou, J. Kopsidas, G. Kourlaba, S. Coffin, T. Zaoutis; Athens, Heraklion, Patras and Larissa (Greece), and Philadelphia (PA, USA)
4th International Congress of Union of European Neonatal and Perinatal Societies (UENPS)
December 11th-14th, 2014, Athens, Greece

BACKGROUND AND AIM: Central Line Associated Bloodstream Infection (CLABSI) is one the most common healthcare-associated infections in hospitalized neonates and is associated with significant mortality, increased length of hospital stay and increased healthcare costs. Since there are limited data about neonatal CLABSI, our aim was to prospectively assess the epidemiology of CLABSIs in 10 Neonatal Intensive Care Units (NICUs) in Greece.

Epidemiology of Antimicrobial Resistance in Neonates with Central Line Associated Bloodstream Infections (CLABSIs) in Greece

K. Mougkou, F. Anatolitou, G. Baroutis, A. Charitou, G. Dimitriou, C. Giannakopoulou, A. Gounaris, J. Kapetanakis, G. Liosis, S. Mellos, G. Nyktari, J. Kopsidas, G. Kourlaba, S. Coffin, T. Zaoutis; Athens, Patras, Heraklion and Larissa (Greece), and Philadelphia (PA, USA)
4th International Congress of Union of European Neonatal and Perinatal Societies (UENPS)
December 11th-14th, 2014, Athens, Greece

BACKGROUND AND AIM: Central Line Associated Bloodstream Infection (CLABSI) is an important cause of mortality in neonates who are critically ill. Many are caused by multi-drug resistant organisms (MDROs) which results in treatment failure [1]. Excessive exposure to antibiotics is thought to increase the risk of colonization or infection with MDROs. The burden of CLABSIs caused by MDROs in hospitalized neonates in Greece is unknown. Our study examined the prevalence of MDRO pathogens causing CLABSIs in neonates.

Crp Elevation Associated with a Positive Blood Culture in Infants Participating in the Neonin Surveillance Network

J. Kopsidas, C. Kortsalioudaki, K. Zannikos, G. Kοurlaba, F. Anatolitou, A. Kent, T. Metsvaht, I. Lutsar, P. Clarke, A. Bedford-Russell, S. Pattnayak, T. Scorrer, T. Zaoutis, PT. Heath, N. Spyridis; on behalf of the Neonatal Infection Surveillance Network (neonIN); London, Norwich, Birmingham, Medway and Portsmouth (UK), Athens (Greece), Tartu (Estonia) and Philadelphia (PA, USA)
4th International Congress of Union of European Neonatal and Perinatal Societies (UENPS)
December 11th-14th, 2014, Athens, Greece

BACKGROUND: Sepsis is the commonest cause of neonatal morbidity and mortality. Clinical and laboratory findings are often non-specific. C-reactive protein (CRP) has been shown to be a useful marker in the diagnosis of neonatal sepsis but with limited data on whether different organisms causing sepsis affect it differently. This study aims to compare maximum CRP (maxCRP) elevation within 48 hours of a positive blood culture across different categories of organisms.

Klebsiella Infection in an European Surveillance Neonatal Network

C. Kortsalioudaki, A. Kent, J. Kopsidas, T. Watts, T. Scorrer, I. Lutsar, M. Turner, P. Clarke, K. Karachristou, A. Collinson, J. Chang, G. Dimitriou, N. Spyridis, T. Zaoutis, PT. Heath; on behalf of the Neonatal Infection Surveillance Network (neonIN); London, Portsmouth, Liverpool, Norwich and Truro (UK), Athens (Greece) and Tartu (Estonia)
4th International Congress of Union of European Neonatal and Perinatal Societies (UENPS)
December 11th-14th, 2014, Athens, Greece

BACKGROUND AND AIMS: Klebsiella spp. are a common cause of hospital-acquired, Gram-negative infections within neonatal units (NNUs) and responsible for outbreaks. This study describes characteristics of invasive Klebsiella spp. infections across European countries participating in a neonatal infection network.

Epidemiology of Neonatal Bacteremia in Greece – Data from a European Surveillance Network

J. Kopsidas, C. Kortsalioudaki, K. Zannikos, K. Karachristou, G. Kοurlaba, F. Anatolitou, N. Lipsou, T. Siachanidou, A. Kent, D. Gkentzi, G. Dimitriou, TE. Zaoutis, PT. Heath, N. Spyridis; on behalf of the Neonatal Infection Surveillance Network (neonIN); Athens and Patras (Greece), London (UK) and Philadelphia (PA, USA)
4th International Congress of Union of European Neonatal and Perinatal Societies (UENPS)
December 11th-14th, 2014, Athens, Greece

BACKGROUND AND AIMS: Neonatal sepsis carries significant morbidity and mortality. Data on the epidemiology of bacteremia leading to sepsis in Greece is limited despite knowledge that the prevalence of healthcare-associated infections, antimicrobial consumption and multi-drug resistant organisms is among the highest in Europe. This study aims to describe the epidemiology of bacteremia in Greek neonatal-units (NNUs), patients’ characteristics and antibiotic-resistance profile as recorded in neonIN.