Crp Elevation Associated with a Positive Blood Culture in Infants Participating in the Neonin Surveillance Network

J. Kopsidas, C. Kortsalioudaki, K. Zannikos, G. Kοurlaba, F. Anatolitou, A. Kent, T. Metsvaht, I. Lutsar, P. Clarke, A. Bedford-Russell, S. Pattnayak, T. Scorrer, T. Zaoutis, PT. Heath, N. Spyridis; on behalf of the Neonatal Infection Surveillance Network (neonIN); London, Norwich, Birmingham, Medway and Portsmouth (UK), Athens (Greece), Tartu (Estonia) and Philadelphia (PA, USA)
4th International Congress of Union of European Neonatal and Perinatal Societies (UENPS)
December 11th-14th, 2014, Athens, Greece

BACKGROUND: Sepsis is the commonest cause of neonatal morbidity and mortality. Clinical and laboratory findings are often non-specific. C-reactive protein (CRP) has been shown to be a useful marker in the diagnosis of neonatal sepsis but with limited data on whether different organisms causing sepsis affect it differently. This study aims to compare maximum CRP (maxCRP) elevation within 48 hours of a positive blood culture across different categories of organisms.

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Epidemiology of Antimicrobial Resistance in Neonates with Central Line Associated Bloodstream Infections (CLABSIs) in Greece

K. Mougkou, F. Anatolitou, G. Baroutis, A. Charitou, G. Dimitriou, C. Giannakopoulou, A. Gounaris, J. Kapetanakis, G. Liosis, S. Mellos, G. Nyktari, J. Kopsidas, G. Kourlaba, S. Coffin, T. Zaoutis; Athens, Patras, Heraklion and Larissa (Greece), and Philadelphia (PA, USA)
4th International Congress of Union of European Neonatal and Perinatal Societies (UENPS)
December 11th-14th, 2014, Athens, Greece

BACKGROUND AND AIM: Central Line Associated Bloodstream Infection (CLABSI) is an important cause of mortality in neonates who are critically ill. Many are caused by multi-drug resistant organisms (MDROs) which results in treatment failure [1]. Excessive exposure to antibiotics is thought to increase the risk of colonization or infection with MDROs. The burden of CLABSIs caused by MDROs in hospitalized neonates in Greece is unknown. Our study examined the prevalence of MDRO pathogens causing CLABSIs in neonates.

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Active Surveillance for Central Line Associated Bloodstream Infections in Hospitalized Neonates in Greece

K. Mougkou, N. Anagnostatou, L. Baglatzi, M. Dilanas, D. Gkentzi, I. Grivea, K. Kaffe, K. Karachristou, A. Kontogianni, L. Lianou, A. Mpilali, C. Petropoulou, Z. Stratiki, I. Zorou, J. Kopsidas, G. Kourlaba, S. Coffin, T. Zaoutis; Athens, Heraklion, Patras and Larissa (Greece), and Philadelphia (PA, USA)
4th International Congress of Union of European Neonatal and Perinatal Societies (UENPS)
December 11th-14th, 2014, Athens, Greece

BACKGROUND AND AIM: Central Line Associated Bloodstream Infection (CLABSI) is one the most common healthcare-associated infections in hospitalized neonates and is associated with significant mortality, increased length of hospital stay and increased healthcare costs. Since there are limited data about neonatal CLABSI, our aim was to prospectively assess the epidemiology of CLABSIs in 10 Neonatal Intensive Care Units (NICUs) in Greece.

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Neonatal Sepsis: A European Neonatal Infection Surveillance Network

C. Kortsalioudaki, D. Gkentzi, S. Vergnano, I. Christopoulou, G. Dimitriou, P.T. Heath, on behalf of the Neonatal Infection Surveillance Network (neonIN)
5th Panhellenic Neonatal
Athens, Greece, May 10-11, 2014

BACKGROUND AND AIMS: Infection is a major cause of neonatal mortality and morbidity. Infections due to Gram-negative (GN) organisms are increasing, although the epidemiology may differ across Europe. The aim of this study was to compare organisms causing neonatal infection in UK and Greek units.

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Central line associated bloodstream infections in hospitalised children in Greece before and after implementation of a prevention bundle

Katerina Mougkou, Despoina Gkentzi , Georgia Kourlaba, Sofia Kouni , Ioannis Kopsidas , Charalampia Nteli , Theoklis Zaoutis, Susan Coffin
5th Panhellenic Neonatal
Athens, Greece, May 10-11, 2014

Data on central line (CL) - associated bloodstream infections (CLABSIs) in neonates and children in Greece are limited. In this study we aimed to assess the epidemiology and microbiology of CLABSIs in children’s hospitals in Greece using an active surveillance system and to assess the impact of a central line bundle on the incidence of CLABSIs.

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