K. Mougkou, A. Michos, K. Spyridopoulou, G.L. Daikos, T. Siahanidou, N. Spyridis, J. Kapetanakis, A. Korkas, M. Anagnostakou, C. Papagaroufalis, G. Baroutis, I. Labadaridis, V. Syriopoulou, T. Zaoutis
30th Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID 2012)
Thessaloniki, Greece, May 8-12, 2012
BACKGROUND: Enterobacteriaceae are among the most common human pathogens causing severe infections such as pneumonia, bacteraemia and meningitis. Escherichia coli and Klebsiella pneumoniae remain the two most frequent causes of Gram - negative blood infections with high mortality rate, especially in neonates. In the past few years, acquired carbapenemases are emerging resistance determinants in Gram - negative bacteria. Carbapenemase – Producing Enterobacteriaceae (CPE) are often resistant to all β - lactam antibiotics and frequently co - resistant to aminoglycosides, trimethoprim/sulfamethoxazole and fluoroquinolones. Carbapenemases have spread in multiple adult hospitals in Greece, where they have attained a high level of endemicity.