A Nationwide Point Prevalence Survey for Assessing Variations in Antibiotic Use Among Neonatal and Paediatric Patients in Greece

N. Spyridis, G. Syridou, K. Mougkou, S. Kouni, E. Roilides, D. Gkentzi, F. Ladomenou, E. Critselis, A. Versporten, T. Zaoutis, on behalf of ARPEC Study Group

31st Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID 2013)
Milan, Italy, May 28-June 1, 2013

BACKGROUND AND AIMS: Within Europe, Greece has among the highest rates of drug resistant organisms and antibiotic consumption. However, the majority of data on antibiotic utilization is derived from adult hospitalized patients. The objective of the study was to determine antibiotic utilization patterns among hospitalized children in Greece.  

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Determinants for Tuberculosis Infection Among Children Investigated with Interferon Gamma Release Assays and Having Contact with Adult Tuberculosis Cases

E. Critselis, N.P. Spyridis, M. Mavrikou, K. Benetatou, K. Karavanaki, C. Bakoula, M.N. Tsolia

31st Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID 2013)
Milan, Italy, May 28-June 1, 2013

BACKGROUND AND AIMS: The predictive factors of latent tuberculosis infection (LTBI) among children remain irresolute. The study evaluated the determinants associated with LTBI among children having contact with adult index cases. 

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Central Line Associated Bloodstream Infections in Two Greek Children`S Hospitals

K. Mougkou, G. Kourlaba, O. Gerodimou, M. Kazantzi, A. Korkas, H. Petropoulou, G. Sideri, S. Vorre, H. Alexandrou, E. Lebessi, E. Critseli, S. Kouni, N. Spyridis, M. Theodoridou, S. Coffin, T.E. Zaoutis

31st Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID 2013)
Milan, Italy, May 28-June 1, 2013

BACKGROUND AND AIMS: Central line associated bloodstream infections (CLABSIs) are the most common healthcare-associated infection in children and are associated with significant morbidity, mortality and hospitalization costs. There are no data available on the epidemiology of CLABSIs in hospitalized children in Greece. The study aim was to determine the rate of CLABSIs in the 2 largest children`s hospitals in Greece.

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Colonization of Neonates with Carbapenemase-Producing Enterobacteriaceae (CPE)

K. Mougkou, A. Michos, K. Spyridopoulou, G.L. Daikos, T. Siahanidou, N. Spyridis, J. Kapetanakis, A. Korkas, M. Anagnostakou, C. Papagaroufalis, G. Baroutis, I. Labadaridis, V. Syriopoulou, T. Zaoutis

30th Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID 2012)
Thessaloniki, Greece, May 8-12, 2012

BACKGROUND: Enterobacteriaceae are among the most common human pathogens causing severe infections such as pneumonia, bacteraemia and meningitis. Escherichia coli and Klebsiella pneumoniae remain the two most frequent causes of Gram - negative blood infections with high mortality rate, especially in neonates. In the past few years, acquired carbapenemases are emerging resistance determinants in Gram - negative bacteria. Carbapenemase – Producing Enterobacteriaceae (CPE) are often resistant to all β - lactam antibiotics and frequently co - resistant to aminoglycosides, trimethoprim/sulfamethoxazole and fluoroquinolones. Carbapenemases have spread in multiple adult hospitals in Greece, where they have attained a high level of endemicity.

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